Kenilworth and Leamington firefighters extricated one individual from the car.
The B4113 Stoneleigh Road between Stoneleigh and the NAEC Stoneleigh entrance is expected to remain blocked for the next few hours, according to police, who made the announcement at 10.30 a.m.
The collision happened at about 7.20am and involved two cars.
Kenilworth Fire Station said: “Crews used hydraulic cutting equipment to safely extricate one casualty by removing the roof of the vehicle, working alongside the Warwickshire and Northamptonshire Air Ambulance, West Midlands Ambulance Service and Warwickshire Police.”
A woman has been taken to hospital.
Officers from the Warwickshire Police Roads Policing Unit are appealing for witnesses to come forward following the collision on the B4113 Stoneleigh Road.
